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SMILES: COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(c3)-c3cnsc3)cc(OC)cc2o1

InChI Key: InChIKey=FFXFDFRJDPWERF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 286432   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM286432 (US9518064, Example 48) Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(c3)-c3cnsc3)cc(OC)cc2o1 Show InChI InChI=1S/C24H18N4O4S2/c1-29-17-7-20(31-12-14-4-3-5-15(6-14)16-10-25-33-13-16)18-9-22(32-21(18)8-17)19-11-28-23(26-19)34-24(27-28)30-2/h3-11,13H,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	65.9	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company; Universite De Montreal US Patent					Assay Description The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...				US Patent US9518064 (2016) BindingDB Entry DOI: 10.7270/Q2TT4SZX
					More data for this Ligand-Target Pair
Proteinase-activated receptor 4 (Homo sapiens (Human))	BDBM286432 (US9518064, Example 48) Show SMILES COc1nn2cc(nc2s1)-c1cc2c(OCc3cccc(c3)-c3cnsc3)cc(OC)cc2o1 Show InChI InChI=1S/C24H18N4O4S2/c1-29-17-7-20(31-12-14-4-3-5-15(6-14)16-10-25-33-13-16)18-9-22(32-21(18)8-17)19-11-28-23(26-19)34-24(27-28)30-2/h3-11,13H,12H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.03	n/a	n/a	n/a	n/a	n/a	25
Bristol-Myers Squibb Company; Universite De Montreal US Patent					Assay Description The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L...				US Patent US9518064 (2016) BindingDB Entry DOI: 10.7270/Q2TT4SZX
					More data for this Ligand-Target Pair