BDBM286448 6-(4-((5-(Furan-3-yl)pyridin-3-yl)methoxy)-6-methoxybenzofuran-2-yl)-2-methoxyimidazo[2,1-b][1,3,4]thiadiazole::US9518064, Example 65
SMILES: COc1nn2cc(nc2s1)-c1cc2c(OCc3cncc(c3)-c3ccoc3)cc(OC)cc2o1
InChI Key: InChIKey=HKIGWTJZBHDXHZ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteinase-activated receptor 4 (Homo sapiens (Human)) | BDBM286448 (6-(4-((5-(Furan-3-yl)pyridin-3-yl)methoxy)-6-metho...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.08 | n/a | n/a | n/a | n/a | n/a | 25 |
Bristol-Myers Squibb Company; Universite De Montreal US Patent | Assay Description The activity of the PAR4 antagonists of the present invention were tested in PAR4 expressing cells by monitoring H-Ala-Phe(4-F)-Pro-Gly-Trp-Leu-Val-L... | US Patent US9518064 (2016) BindingDB Entry DOI: 10.7270/Q2TT4SZX | |||||||||||
More data for this Ligand-Target Pair |