BDBM28689 2-({3-[(6-chloro-1H-indole-1-)sulfonyl]benzene}amido)-5-methylbenzoic acid::Anthranilic acid deriv., 27

SMILES: Cc1ccc(NC(=O)c2cccc(c2)S(=O)(=O)n2ccc3ccc(Cl)cc23)c(c1)C(O)=O

InChI Key: InChIKey=ATXPCFTUFHGWSH-UHFFFAOYSA-N

Data: 6 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 28689   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM28689 (2-({3-[(6-chloro-1H-indole-1-)sulfonyl]benzene}ami...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)S(=O)(=O)n2ccc3ccc(Cl)cc23)c(c1)C(O)=O Show InChI InChI=1S/C23H17ClN2O5S/c1-14-5-8-20(19(11-14)23(28)29)25-22(27)16-3-2-4-18(12-16)32(30,31)26-10-9-15-6-7-17(24)13-21(15)26/h2-13H,1H3,(H,25,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	200	n/a	n/a	n/a	n/a
GSK					Assay Description Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...				Bioorg Med Chem Lett 18: 5018-22 (2008) Article DOI: 10.1016/j.bmcl.2008.08.011 BindingDB Entry DOI: 10.7270/Q2WD3XWS
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM28689 (2-({3-[(6-chloro-1H-indole-1-)sulfonyl]benzene}ami...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)S(=O)(=O)n2ccc3ccc(Cl)cc23)c(c1)C(O)=O Show InChI InChI=1S/C23H17ClN2O5S/c1-14-5-8-20(19(11-14)23(28)29)25-22(27)16-3-2-4-18(12-16)32(30,31)26-10-9-15-6-7-17(24)13-21(15)26/h2-13H,1H3,(H,25,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...				Bioorg Med Chem Lett 18: 5018-22 (2008) Article DOI: 10.1016/j.bmcl.2008.08.011 BindingDB Entry DOI: 10.7270/Q2WD3XWS
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM28689 (2-({3-[(6-chloro-1H-indole-1-)sulfonyl]benzene}ami...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)S(=O)(=O)n2ccc3ccc(Cl)cc23)c(c1)C(O)=O Show InChI InChI=1S/C23H17ClN2O5S/c1-14-5-8-20(19(11-14)23(28)29)25-22(27)16-3-2-4-18(12-16)32(30,31)26-10-9-15-6-7-17(24)13-21(15)26/h2-13H,1H3,(H,25,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional Aut£noma de M£xico Curated by ChEMBL					Assay Description Agonist activity at PPARgamma				Bioorg Med Chem 20: 3523-32 (2012) Article DOI: 10.1016/j.bmc.2012.04.005 BindingDB Entry DOI: 10.7270/Q2MP54B4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM28689 (2-({3-[(6-chloro-1H-indole-1-)sulfonyl]benzene}ami...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)S(=O)(=O)n2ccc3ccc(Cl)cc23)c(c1)C(O)=O Show InChI InChI=1S/C23H17ClN2O5S/c1-14-5-8-20(19(11-14)23(28)29)25-22(27)16-3-2-4-18(12-16)32(30,31)26-10-9-15-6-7-17(24)13-21(15)26/h2-13H,1H3,(H,25,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional Aut£noma de M£xico Curated by ChEMBL					Assay Description Agonist activity at PPARalpha				Bioorg Med Chem 20: 3523-32 (2012) Article DOI: 10.1016/j.bmc.2012.04.005 BindingDB Entry DOI: 10.7270/Q2MP54B4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM28689 (2-({3-[(6-chloro-1H-indole-1-)sulfonyl]benzene}ami...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)S(=O)(=O)n2ccc3ccc(Cl)cc23)c(c1)C(O)=O Show InChI InChI=1S/C23H17ClN2O5S/c1-14-5-8-20(19(11-14)23(28)29)25-22(27)16-3-2-4-18(12-16)32(30,31)26-10-9-15-6-7-17(24)13-21(15)26/h2-13H,1H3,(H,25,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.0	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional Aut£noma de M£xico Curated by ChEMBL					Assay Description Agonist activity at PPARdelta				Bioorg Med Chem 20: 3523-32 (2012) Article DOI: 10.1016/j.bmc.2012.04.005 BindingDB Entry DOI: 10.7270/Q2MP54B4
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM28689 (2-({3-[(6-chloro-1H-indole-1-)sulfonyl]benzene}ami...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)S(=O)(=O)n2ccc3ccc(Cl)cc23)c(c1)C(O)=O Show InChI InChI=1S/C23H17ClN2O5S/c1-14-5-8-20(19(11-14)23(28)29)25-22(27)16-3-2-4-18(12-16)32(30,31)26-10-9-15-6-7-17(24)13-21(15)26/h2-13H,1H3,(H,25,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...				Bioorg Med Chem Lett 18: 5018-22 (2008) Article DOI: 10.1016/j.bmcl.2008.08.011 BindingDB Entry DOI: 10.7270/Q2WD3XWS
					More data for this Ligand-Target Pair