BDBM2870 3-(5-bromopyridin-2-yl)-1-[3-(2,6-difluorophenyl)-3-oxopropyl]thiourea::PETT deriv. 20

SMILES: Fc1cccc(F)c1C(=O)CCNC(=S)Nc1ccc(Br)cn1

InChI Key: InChIKey=BOOFKKBANNNNAY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Reverse Transcriptase (Human immunodeficiency virus type 1)	BDBM2870 (3-(5-bromopyridin-2-yl)-1-[3-(2,6-difluorophenyl)-...) Show SMILES Fc1cccc(F)c1C(=O)CCNC(=S)Nc1ccc(Br)cn1 Show InChI InChI=1S/C15H12BrF2N3OS/c16-9-4-5-13(20-8-9)21-15(23)19-7-6-12(22)14-10(17)2-1-3-11(14)18/h1-5,8H,6-7H2,(H2,19,20,21,23)	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	7.8	37
Medivir AB					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				Bioorg Med Chem Lett 10: 265-8 (2000) Article DOI: 10.1016/s0960-894x(99)00675-7 BindingDB Entry DOI: 10.7270/Q2DF6PDR
					More data for this Ligand-Target Pair