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SMILES: Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=S1(=O)CCN(CC1)C(=O)OC(C)(C)C

InChI Key: InChIKey=ALHIARXSDDUOII-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287561   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM287561
PNG
(US9567324, 1)
Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=S1(=O)CCN(CC1)C(=O)OC(C)(C)C
Show InChI InChI=1S/C29H30N4O6S/c1-20-10-13-38-25(20)27(35)31-24-7-5-6-21(17-24)8-9-22-16-23(19-30-18-22)26(34)32-40(37)14-11-33(12-15-40)28(36)39-29(2,3)4/h5-7,10,13,16-19H,11-12,14-15H2,1-4H3,(H,31,35)
PDB
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NCI pathway
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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/a7.4n/a



ALLERGAN, INC.

US Patent


Assay Description
Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...

US Patent US9567324 (2017)


BindingDB Entry DOI: 10.7270/Q2JD4ZTK
More data for this
Ligand-Target Pair