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SMILES: CCOC(=O)CCNC(=O)N1CCS(=O)(CC1)=NC(=O)c1cncc(c1)C#Cc1cccc(NC(=O)c2occc2C)c1

InChI Key: InChIKey=VGNHZUVROMQOQX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287564   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM287564
PNG
(US9567324, 4)
Show SMILES CCOC(=O)CCNC(=O)N1CCS(=O)(CC1)=NC(=O)c1cncc(c1)C#Cc1cccc(NC(=O)c2occc2C)c1
Show InChI InChI=1S/C30H31N5O7S/c1-3-41-26(36)9-11-32-30(39)35-12-15-43(40,16-13-35)34-28(37)24-17-23(19-31-20-24)8-7-22-5-4-6-25(18-22)33-29(38)27-21(2)10-14-42-27/h4-6,10,14,17-20H,3,9,11-13,15-16H2,1-2H3,(H,32,39)(H,33,38)
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KEGG

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US Patent
n/an/a 3n/an/an/an/a7.4n/a



ALLERGAN, INC.

US Patent


Assay Description
Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...

US Patent US9567324 (2017)


BindingDB Entry DOI: 10.7270/Q2JD4ZTK
More data for this
Ligand-Target Pair