BDBM287565 US9567324, 5

SMILES: CCOC(=O)CCCNC(=O)N1CCS(=O)(CC1)=NC(=O)c1cncc(c1)C#Cc1cccc(NC(=O)c2occc2C)c1

InChI Key: InChIKey=JJLBHSOHNGAGAY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM287565 (US9567324, 5) Show SMILES CCOC(=O)CCCNC(=O)N1CCS(=O)(CC1)=NC(=O)c1cncc(c1)C#Cc1cccc(NC(=O)c2occc2C)c1 Show InChI InChI=1S/C31H33N5O7S/c1-3-42-27(37)8-5-12-33-31(40)36-13-16-44(41,17-14-36)35-29(38)25-18-24(20-32-21-25)10-9-23-6-4-7-26(19-23)34-30(39)28-22(2)11-15-43-28/h4,6-7,11,15,18-21H,3,5,8,12-14,16-17H2,1-2H3,(H,33,40)(H,34,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
ALLERGAN, INC. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				US Patent US9567324 (2017) BindingDB Entry DOI: 10.7270/Q2JD4ZTK
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