BDBM287567 US9567324, 7

SMILES: Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=S1(=O)CCN(CC1)C(=O)NCCCC(O)=O

InChI Key: InChIKey=LSWFETUDMPCNDW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM287567 (US9567324, 7) Show SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)C(=O)N=S1(=O)CCN(CC1)C(=O)NCCCC(O)=O Show InChI InChI=1S/C29H29N5O7S/c1-20-9-13-41-26(20)28(38)32-24-5-2-4-21(17-24)7-8-22-16-23(19-30-18-22)27(37)33-42(40)14-11-34(12-15-42)29(39)31-10-3-6-25(35)36/h2,4-5,9,13,16-19H,3,6,10-12,14-15H2,1H3,(H,31,39)(H,32,38)(H,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	n/a
ALLERGAN, INC. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				US Patent US9567324 (2017) BindingDB Entry DOI: 10.7270/Q2JD4ZTK
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