BDBM28769 2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-5-phenyl-1,2-oxazol-3-yl)phenyl]acetic acid::trisubstituted isoxazole, 17d

SMILES: OC(=O)Cc1cccc(c1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1

InChI Key: InChIKey=HINPKGVWVQYESB-UHFFFAOYSA-N

Data: 3 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 28769   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM28769 (2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...) Show SMILES OC(=O)Cc1cccc(c1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C26H20Cl2N2O5/c27-19-9-10-21(20(28)15-19)34-12-11-29-26(33)23-24(18-8-4-5-16(13-18)14-22(31)32)30-35-25(23)17-6-2-1-3-7-17/h1-10,13,15H,11-12,14H2,(H,29,33)(H,31,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
GNF					Assay Description EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...				Bioorg Med Chem Lett 16: 5488-92 (2006) Article DOI: 10.1016/j.bmcl.2006.08.052 BindingDB Entry DOI: 10.7270/Q23X84Z3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM28769 (2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...) Show SMILES OC(=O)Cc1cccc(c1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C26H20Cl2N2O5/c27-19-9-10-21(20(28)15-19)34-12-11-29-26(33)23-24(18-8-4-5-16(13-18)14-22(31)32)30-35-25(23)17-6-2-1-3-7-17/h1-10,13,15H,11-12,14H2,(H,29,33)(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GNF					Assay Description EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...				Bioorg Med Chem Lett 16: 5488-92 (2006) Article DOI: 10.1016/j.bmcl.2006.08.052 BindingDB Entry DOI: 10.7270/Q23X84Z3
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM28769 (2-[3-(4-{[2-(2,4-dichlorophenoxy)ethyl]carbamoyl}-...) Show SMILES OC(=O)Cc1cccc(c1)-c1noc(c1C(=O)NCCOc1ccc(Cl)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C26H20Cl2N2O5/c27-19-9-10-21(20(28)15-19)34-12-11-29-26(33)23-24(18-8-4-5-16(13-18)14-22(31)32)30-35-25(23)17-6-2-1-3-7-17/h1-10,13,15H,11-12,14H2,(H,29,33)(H,31,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
GNF					Assay Description EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...				Bioorg Med Chem Lett 16: 5488-92 (2006) Article DOI: 10.1016/j.bmcl.2006.08.052 BindingDB Entry DOI: 10.7270/Q23X84Z3
					More data for this Ligand-Target Pair