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SMILES: CC(C)c1cc2ccc(c(-c3cc(C)c4[nH]ncc4c3)n2n1)C(F)(F)F

InChI Key: InChIKey=WLXZXBAGVKKKJZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288256   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent calcium channel gamma-8 subunit


(Homo sapiens (Human))		BDBM288256
PNG
(5-(2-Isopropyl-6-(trifluoromethyl)pyrazolo[1,5-a]p...)
Show SMILES CC(C)c1cc2ccc(c(-c3cc(C)c4[nH]ncc4c3)n2n1)C(F)(F)F
Show InChI InChI=1S/C19H17F3N4/c1-10(2)16-8-14-4-5-15(19(20,21)22)18(26(14)25-16)12-6-11(3)17-13(7-12)9-23-24-17/h4-10H,1-3H3,(H,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.0790n/an/an/an/a7.4n/a



Janssen Pharmaceutica NV

US Patent


Assay Description
This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...

US Patent US10087185 (2018)


BindingDB Entry DOI: 10.7270/Q2QZ2D0H
More data for this
Ligand-Target Pair