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SMILES: CCC(C)(C)C(=O)N1CCCC1c1cc(F)cc(F)c1F

InChI Key: InChIKey=DEEIQPQIDFEGCF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288686   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-interacting serine/threonine-protein kinase 1


(Homo sapiens (Human))		BDBM288686
PNG
(TC001124 | US10092529, Compound 10)
Show SMILES CCC(C)(C)C(=O)N1CCCC1c1cc(F)cc(F)c1F
Show InChI InChI=1S/C16H20F3NO/c1-4-16(2,3)15(21)20-7-5-6-13(20)11-8-10(17)9-12(18)14(11)19/h8-9,13H,4-7H2,1-3H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 22.5 -10.4n/an/an/an/an/an/a25



National Institute of Biological Sciences, Beijing

US Patent


Assay Description
Materials: Recombinant full-length RIPK1 protein with N-terminal GST-tag (Cat#R07-34G) was purchased from SignalChem. The ADP-Glo kinase assay kit (C...

US Patent US10092529 (2018)


BindingDB Entry DOI: 10.7270/Q26W9D35
More data for this
Ligand-Target Pair