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SMILES: CC[C@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=HILPOOWQEBWFGB-JOYOIKCWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28933   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1


(Homo sapiens (Human))		BDBM28933
PNG
((2S,3S)-1-hydroxy-3-methyl-N-[4-(trifluoromethyl)p...)
Show SMILES CC[C@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(cc1)C(F)(F)F |r|
Show InChI InChI=1S/C13H18F3NO3S/c1-3-9(2)12(8-18)17-21(19,20)11-6-4-10(5-7-11)13(14,15)16/h4-7,9,12,17-18H,3,8H2,1-2H3/t9-,12+/m0/s1
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MMDB

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Similars
Article
PubMed
n/an/an/an/a 1.31E+4n/an/an/an/a



Wyeth Research



Assay Description
A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...

Bioorg Med Chem Lett 18: 4232-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.064
BindingDB Entry DOI: 10.7270/Q26Q1VJM
More data for this
Ligand-Target Pair