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SMILES: CC[C@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(OC(C)(F)F)cc1

InChI Key: InChIKey=QYLYMDBGZXWVFU-GXFFZTMASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28937   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1


(Homo sapiens (Human))		BDBM28937
PNG
((2S,3S)-N-[4-(1,1-difluoroethoxy)phenyl]-1-hydroxy...)
Show SMILES CC[C@H](C)[C@@H](CO)NS(=O)(=O)c1ccc(OC(C)(F)F)cc1 |r|
Show InChI InChI=1S/C14H21F2NO4S/c1-4-10(2)13(9-18)17-22(19,20)12-7-5-11(6-8-12)21-14(3,15)16/h5-8,10,13,17-18H,4,9H2,1-3H3/t10-,13+/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 2.35E+4n/an/an/an/a



Wyeth Research



Assay Description
A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...

Bioorg Med Chem Lett 18: 4232-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.064
BindingDB Entry DOI: 10.7270/Q26Q1VJM
More data for this
Ligand-Target Pair