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SMILES: NC1CCCC1N1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O

InChI Key: InChIKey=OZRYRXLHUXBIMR-YUVKLTJASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 290378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase-1 (Homo sapiens (Human))	BDBM290378 ((3R,4S)-3-amino-1-(2-aminocyclopentyl)-4-(3- boron...) Show SMILES NC1CCCC1N1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O |r| Show InChI InChI=1S/C13H26BN3O4/c15-10-4-1-5-11(10)17-7-9(3-2-6-14(20)21)13(16,8-17)12(18)19/h9-11,20-21H,1-8,15-16H2,(H,18,19)/t9-,10?,11?,13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM290378 ((3R,4S)-3-amino-1-(2-aminocyclopentyl)-4-(3- boron...) Show SMILES NC1CCCC1N1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O |r| Show InChI InChI=1S/C13H26BN3O4/c15-10-4-1-5-11(10)17-7-9(3-2-6-14(20)21)13(16,8-17)12(18)19/h9-11,20-21H,1-8,15-16H2,(H,18,19)/t9-,10?,11?,13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10603330 (2020)
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290378 ((3R,4S)-3-amino-1-(2-aminocyclopentyl)-4-(3- boron...) Show SMILES NC1CCCC1N1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O |r| Show InChI InChI=1S/C13H26BN3O4/c15-10-4-1-5-11(10)17-7-9(3-2-6-14(20)21)13(16,8-17)12(18)19/h9-11,20-21H,1-8,15-16H2,(H,18,19)/t9-,10?,11?,13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10603330 (2020)
					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM290378 ((3R,4S)-3-amino-1-(2-aminocyclopentyl)-4-(3- boron...) Show SMILES NC1CCCC1N1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O |r| Show InChI InChI=1S/C13H26BN3O4/c15-10-4-1-5-11(10)17-7-9(3-2-6-14(20)21)13(16,8-17)12(18)19/h9-11,20-21H,1-8,15-16H2,(H,18,19)/t9-,10?,11?,13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair