BDBM290384 (3R,4S)-1-((1H-imidazol-4-yl)methyl)-3-amino-4-(3- boronopropyl)pyrrolidine-3-carboxylic acid::US10098902, Example 20

SMILES: N[C@]1(CN(Cc2c[nH]cn2)C[C@@H]1CCCB(O)O)C(O)=O

InChI Key:

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 290384   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM290384 ((3R,4S)-1-((1H-imidazol-4-yl)methyl)-3-amino-4-(3-...) Show SMILES N[C@]1(CN(Cc2c[nH]cn2)C[C@@H]1CCCB(O)O)C(O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	625	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290384 ((3R,4S)-1-((1H-imidazol-4-yl)methyl)-3-amino-4-(3-...) Show SMILES N[C@]1(CN(Cc2c[nH]cn2)C[C@@H]1CCCB(O)O)C(O)=O |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair