null

SMILES: N[C@]1(CN(CC2CCCCN2)C[C@@H]1CCCB(O)O)C(O)=O

InChI Key: InChIKey=XALRSRWVBVPEPE-PSIKVXPXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 290385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase-1 (Homo sapiens (Human))	BDBM290385 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin-2-...) Show SMILES N[C@]1(CN(CC2CCCCN2)C[C@@H]1CCCB(O)O)C(O)=O |r| Show InChI InChI=1S/C14H28BN3O4/c16-14(13(19)20)10-18(9-12-5-1-2-7-17-12)8-11(14)4-3-6-15(21)22/h11-12,17,21-22H,1-10,16H2,(H,19,20)/t11-,12?,14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM290385 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin-2-...) Show SMILES N[C@]1(CN(CC2CCCCN2)C[C@@H]1CCCB(O)O)C(O)=O |r| Show InChI InChI=1S/C14H28BN3O4/c16-14(13(19)20)10-18(9-12-5-1-2-7-17-12)8-11(14)4-3-6-15(21)22/h11-12,17,21-22H,1-10,16H2,(H,19,20)/t11-,12?,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM290385 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin-2-...) Show SMILES N[C@]1(CN(CC2CCCCN2)C[C@@H]1CCCB(O)O)C(O)=O |r| Show InChI InChI=1S/C14H28BN3O4/c16-14(13(19)20)10-18(9-12-5-1-2-7-17-12)8-11(14)4-3-6-15(21)22/h11-12,17,21-22H,1-10,16H2,(H,19,20)/t11-,12?,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM290385 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin-2-...) Show SMILES N[C@]1(CN(CC2CCCCN2)C[C@@H]1CCCB(O)O)C(O)=O |r| Show InChI InChI=1S/C14H28BN3O4/c16-14(13(19)20)10-18(9-12-5-1-2-7-17-12)8-11(14)4-3-6-15(21)22/h11-12,17,21-22H,1-10,16H2,(H,19,20)/t11-,12?,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10603330 (2020)
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290385 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin-2-...) Show SMILES N[C@]1(CN(CC2CCCCN2)C[C@@H]1CCCB(O)O)C(O)=O |r| Show InChI InChI=1S/C14H28BN3O4/c16-14(13(19)20)10-18(9-12-5-1-2-7-17-12)8-11(14)4-3-6-15(21)22/h11-12,17,21-22H,1-10,16H2,(H,19,20)/t11-,12?,14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290385 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(piperidin-2-...) Show SMILES N[C@]1(CN(CC2CCCCN2)C[C@@H]1CCCB(O)O)C(O)=O |r| Show InChI InChI=1S/C14H28BN3O4/c16-14(13(19)20)10-18(9-12-5-1-2-7-17-12)8-11(14)4-3-6-15(21)22/h11-12,17,21-22H,1-10,16H2,(H,19,20)/t11-,12?,14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10603330 (2020)
					More data for this Ligand-Target Pair