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SMILES: N[C@]1(CN(C[C@@H]1CCCB(O)O)C(=O)C1Cc2ccccc2CN1)C(O)=O

InChI Key: InChIKey=WFEBUUXHNXIERH-RARQCXRASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 290417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase-1 (Homo sapiens (Human))	BDBM290417 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(1,2,3,4- tet...) Show SMILES N[C@]1(CN(C[C@@H]1CCCB(O)O)C(=O)C1Cc2ccccc2CN1)C(O)=O |r| Show InChI InChI=1S/C18H26BN3O5/c20-18(17(24)25)11-22(10-14(18)6-3-7-19(26)27)16(23)15-8-12-4-1-2-5-13(12)9-21-15/h1-2,4-5,14-15,21,26-27H,3,6-11,20H2,(H,24,25)/t14-,15?,18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM290417 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(1,2,3,4- tet...) Show SMILES N[C@]1(CN(C[C@@H]1CCCB(O)O)C(=O)C1Cc2ccccc2CN1)C(O)=O |r| Show InChI InChI=1S/C18H26BN3O5/c20-18(17(24)25)11-22(10-14(18)6-3-7-19(26)27)16(23)15-8-12-4-1-2-5-13(12)9-21-15/h1-2,4-5,14-15,21,26-27H,3,6-11,20H2,(H,24,25)/t14-,15?,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	625	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM290417 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(1,2,3,4- tet...) Show SMILES N[C@]1(CN(C[C@@H]1CCCB(O)O)C(=O)C1Cc2ccccc2CN1)C(O)=O |r| Show InChI InChI=1S/C18H26BN3O5/c20-18(17(24)25)11-22(10-14(18)6-3-7-19(26)27)16(23)15-8-12-4-1-2-5-13(12)9-21-15/h1-2,4-5,14-15,21,26-27H,3,6-11,20H2,(H,24,25)/t14-,15?,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	625	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM290417 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(1,2,3,4- tet...) Show SMILES N[C@]1(CN(C[C@@H]1CCCB(O)O)C(=O)C1Cc2ccccc2CN1)C(O)=O |r| Show InChI InChI=1S/C18H26BN3O5/c20-18(17(24)25)11-22(10-14(18)6-3-7-19(26)27)16(23)15-8-12-4-1-2-5-13(12)9-21-15/h1-2,4-5,14-15,21,26-27H,3,6-11,20H2,(H,24,25)/t14-,15?,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10603330 (2020)
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290417 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(1,2,3,4- tet...) Show SMILES N[C@]1(CN(C[C@@H]1CCCB(O)O)C(=O)C1Cc2ccccc2CN1)C(O)=O |r| Show InChI InChI=1S/C18H26BN3O5/c20-18(17(24)25)11-22(10-14(18)6-3-7-19(26)27)16(23)15-8-12-4-1-2-5-13(12)9-21-15/h1-2,4-5,14-15,21,26-27H,3,6-11,20H2,(H,24,25)/t14-,15?,18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290417 ((3R,4S)-3-amino-4-(3-boronopropyl)-1-(1,2,3,4- tet...) Show SMILES N[C@]1(CN(C[C@@H]1CCCB(O)O)C(=O)C1Cc2ccccc2CN1)C(O)=O |r| Show InChI InChI=1S/C18H26BN3O5/c20-18(17(24)25)11-22(10-14(18)6-3-7-19(26)27)16(23)15-8-12-4-1-2-5-13(12)9-21-15/h1-2,4-5,14-15,21,26-27H,3,6-11,20H2,(H,24,25)/t14-,15?,18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10603330 (2020)
					More data for this Ligand-Target Pair