BDBM290427 (1S,2S,4S)-1-amino-2-(3-boronopropyl)-4- (dimethylamino)cyclopentanecarboxylic acid::US10098902, Example 63::US10603330, Example 63

SMILES: CN(C)[C@H]1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O

InChI Key: InChIKey=PAISJDKZPQIYMP-QXEWZRGKSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 290427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase-1 (Homo sapiens (Human))	BDBM290427 ((1S,2S,4S)-1-amino-2-(3-boronopropyl)-4- (dimethyl...) Show SMILES CN(C)[C@H]1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O |r| Show InChI InChI=1S/C11H23BN2O4/c1-14(2)9-6-8(4-3-5-12(17)18)11(13,7-9)10(15)16/h8-9,17-18H,3-7,13H2,1-2H3,(H,15,16)/t8-,9-,11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM290427 ((1S,2S,4S)-1-amino-2-(3-boronopropyl)-4- (dimethyl...) Show SMILES CN(C)[C@H]1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O |r| Show InChI InChI=1S/C11H23BN2O4/c1-14(2)9-6-8(4-3-5-12(17)18)11(13,7-9)10(15)16/h8-9,17-18H,3-7,13H2,1-2H3,(H,15,16)/t8-,9-,11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10603330 (2020)
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290427 ((1S,2S,4S)-1-amino-2-(3-boronopropyl)-4- (dimethyl...) Show SMILES CN(C)[C@H]1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O |r| Show InChI InChI=1S/C11H23BN2O4/c1-14(2)9-6-8(4-3-5-12(17)18)11(13,7-9)10(15)16/h8-9,17-18H,3-7,13H2,1-2H3,(H,15,16)/t8-,9-,11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10603330 (2020)
					More data for this Ligand-Target Pair
Arginase-2, mitochondrial (Homo sapiens (Human))	BDBM290427 ((1S,2S,4S)-1-amino-2-(3-boronopropyl)-4- (dimethyl...) Show SMILES CN(C)[C@H]1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O |r| Show InChI InChI=1S/C11H23BN2O4/c1-14(2)9-6-8(4-3-5-12(17)18)11(13,7-9)10(15)16/h8-9,17-18H,3-7,13H2,1-2H3,(H,15,16)/t8-,9-,11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair