BDBM29063 lactam-based compound, 12b

SMILES: CCN1CCc2c(nn(c2-c2ccc(Cl)cc2)-c2ccccc2Cl)C1=O

InChI Key: InChIKey=QOWZWLUZYDFLKV-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29063   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM29063 (lactam-based compound, 12b) Show SMILES CCN1CCc2c(nn(c2-c2ccc(Cl)cc2)-c2ccccc2Cl)C1=O Show InChI InChI=1S/C20H17Cl2N3O/c1-2-24-12-11-15-18(20(24)26)23-25(17-6-4-3-5-16(17)22)19(15)13-7-9-14(21)10-8-13/h3-10H,2,11-12H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.70	-11.5	n/a	n/a	25	n/a	n/a	7.4	30
Pfizer					Assay Description IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...				J Med Chem 52: 2652-5 (2009) Article DOI: 10.1021/jm900255t BindingDB Entry DOI: 10.7270/Q2F47MGD
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM29063 (lactam-based compound, 12b) Show SMILES CCN1CCc2c(nn(c2-c2ccc(Cl)cc2)-c2ccccc2Cl)C1=O Show InChI InChI=1S/C20H17Cl2N3O/c1-2-24-12-11-15-18(20(24)26)23-25(17-6-4-3-5-16(17)22)19(15)13-7-9-14(21)10-8-13/h3-10H,2,11-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.34E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...				J Med Chem 52: 2652-5 (2009) Article DOI: 10.1021/jm900255t BindingDB Entry DOI: 10.7270/Q2F47MGD
					More data for this Ligand-Target Pair