BDBM29067 lactam-based compound, 12f

SMILES: Clc1ccc(cc1)-c1c2CCN(C3CCCC3)C(=O)c2nn1-c1ccccc1Cl

InChI Key: InChIKey=FQJAKVRJSIYTAP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM29067 (lactam-based compound, 12f) Show SMILES Clc1ccc(cc1)-c1c2CCN(C3CCCC3)C(=O)c2nn1-c1ccccc1Cl Show InChI InChI=1S/C23H21Cl2N3O/c24-16-11-9-15(10-12-16)22-18-13-14-27(17-5-1-2-6-17)23(29)21(18)26-28(22)20-8-4-3-7-19(20)25/h3-4,7-12,17H,1-2,5-6,13-14H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	24	-10.6	n/a	n/a	n/a	n/a	n/a	7.4	30
Pfizer					Assay Description IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...				J Med Chem 52: 2652-5 (2009) Article DOI: 10.1021/jm900255t BindingDB Entry DOI: 10.7270/Q2F47MGD
					More data for this Ligand-Target Pair