BDBM292545 N-((S)-2-(diethylamino)propyl)-2-(((S)-2-hydroxypropyl)amino)-6-(5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl)isonicotinamide::US10100058, Example 201

SMILES: CCN(CC)[C@@H](C)CNC(=O)c1cc(NC[C@H](C)O)nc(c1)-c1cnn2ccc(nc12)-c1cccs1

InChI Key: InChIKey=LKMDLWBQTSEDMN-ROUUACIJSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292545 (N-((S)-2-(diethylamino)propyl)-2-(((S)-2-hydroxypr...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(NC[C@H](C)O)nc(c1)-c1cnn2ccc(nc12)-c1cccs1 |r| Show InChI InChI=1S/C26H33N7O2S/c1-5-32(6-2)17(3)14-28-26(35)19-12-22(30-24(13-19)27-15-18(4)34)20-16-29-33-10-9-21(31-25(20)33)23-8-7-11-36-23/h7-13,16-18,34H,5-6,14-15H2,1-4H3,(H,27,30)(H,28,35)/t17-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	27.1	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292545 (N-((S)-2-(diethylamino)propyl)-2-(((S)-2-hydroxypr...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(NC[C@H](C)O)nc(c1)-c1cnn2ccc(nc12)-c1cccs1 |r| Show InChI InChI=1S/C26H33N7O2S/c1-5-32(6-2)17(3)14-28-26(35)19-12-22(30-24(13-19)27-15-18(4)34)20-16-29-33-10-9-21(31-25(20)33)23-8-7-11-36-23/h7-13,16-18,34H,5-6,14-15H2,1-4H3,(H,27,30)(H,28,35)/t17-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair