BDBM292661 2-((S)-3-aminopyrrolidin-1-yl)-N-((S)-2-(diethylamino)propyl)-6-(5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl)isonicotinamide::US10100058, Example 317

SMILES: CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC[C@H](N)C1

InChI Key: InChIKey=IQFCWPZFRWBDMC-ICSRJNTNSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292661 (2-((S)-3-aminopyrrolidin-1-yl)-N-((S)-2-(diethylam...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C27H34N8OS/c1-4-33(5-2)18(3)15-29-27(36)19-13-23(31-25(14-19)34-10-8-20(28)17-34)21-16-30-35-11-9-22(32-26(21)35)24-7-6-12-37-24/h6-7,9,11-14,16,18,20H,4-5,8,10,15,17,28H2,1-3H3,(H,29,36)/t18-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	68.7	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292661 (2-((S)-3-aminopyrrolidin-1-yl)-N-((S)-2-(diethylam...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C27H34N8OS/c1-4-33(5-2)18(3)15-29-27(36)19-13-23(31-25(14-19)34-10-8-20(28)17-34)21-16-30-35-11-9-22(32-26(21)35)24-7-6-12-37-24/h6-7,9,11-14,16,18,20H,4-5,8,10,15,17,28H2,1-3H3,(H,29,36)/t18-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair