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SMILES: CCN(CC)[C@@H](C)CNC(=O)c1cc(OCC(C)(C)O)nc(c1)-c1cnn2ccc(nc12)-c1cccs1

InChI Key: InChIKey=UMPQDIBDTHVMSY-SFHVURJKSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292697   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM292697
PNG
((S)-N-(2-(diethylamino)propyl)-2-(2-hydroxy-2-meth...)
Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(OCC(C)(C)O)nc(c1)-c1cnn2ccc(nc12)-c1cccs1 |r|
Show InChI InChI=1S/C27H34N6O3S/c1-6-32(7-2)18(3)15-28-26(34)19-13-22(30-24(14-19)36-17-27(4,5)35)20-16-29-33-11-10-21(31-25(20)33)23-9-8-12-37-23/h8-14,16,18,35H,6-7,15,17H2,1-5H3,(H,28,34)/t18-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 38.4n/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...


US Patent US10100058 (2018)


BindingDB Entry DOI: 10.7270/Q2V98B4F
More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta


(Homo sapiens (Human))
BDBM292697
PNG
((S)-N-(2-(diethylamino)propyl)-2-(2-hydroxy-2-meth...)
Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(OCC(C)(C)O)nc(c1)-c1cnn2ccc(nc12)-c1cccs1 |r|
Show InChI InChI=1S/C27H34N6O3S/c1-6-32(7-2)18(3)15-28-26(34)19-13-22(30-24(14-19)36-17-27(4,5)35)20-16-29-33-11-10-21(31-25(20)33)23-9-8-12-37-23/h8-14,16,18,35H,6-7,15,17H2,1-5H3,(H,28,34)/t18-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.100n/an/an/an/an/an/a



Gilead Sciences, Inc.

US Patent


Assay Description
The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...


US Patent US10100058 (2018)


BindingDB Entry DOI: 10.7270/Q2V98B4F
More data for this
Ligand-Target Pair