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BDBM293274 US10106504, Example 11

SMILES: Cc1nc(CNCC2CCOCC2)c(-c2ccc(OCCc3ccc(F)cc3)cc2)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O

InChI Key: InChIKey=UGRFDKPVYSWHGB-FAIXQHPJSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293274   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HIV-1 Protease Chain A


(Human immunodeficiency virus type 1)		BDBM293274
PNG
(US10106504, Example 11)
Show SMILES Cc1nc(CNCC2CCOCC2)c(-c2ccc(OCCc3ccc(F)cc3)cc2)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C42H49FN2O6/c1-27-37(40(41(46)47)51-42(2,3)4)39(32-11-16-36-31(24-32)6-5-20-50-36)38(35(45-27)26-44-25-29-17-21-48-22-18-29)30-9-14-34(15-10-30)49-23-19-28-7-12-33(43)13-8-28/h7-16,24,29,40,44H,5-6,17-23,25-26H2,1-4H3,(H,46,47)/t40-/m0/s1
PDB

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AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<100n/an/a7.55n/a



ViiV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10106504 (2018)


BindingDB Entry DOI: 10.7270/Q2BC41K2
More data for this
Ligand-Target Pair