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BDBM293277 US10106504, Example 14

SMILES: Cc1nc(CO)c(-c2ccc(OCCc3ccc(F)cc3)cc2)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O

InChI Key: InChIKey=RAWLHWWAEJUJLK-UMSFTDKQSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293277   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HIV-1 Protease Chain A


(Human immunodeficiency virus type 1)		BDBM293277
PNG
(US10106504, Example 14)
Show SMILES Cc1nc(CO)c(-c2ccc(OCCc3ccc(F)cc3)cc2)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C36H38FNO6/c1-22-31(34(35(40)41)44-36(2,3)4)33(26-11-16-30-25(20-26)6-5-18-43-30)32(29(21-39)38-22)24-9-14-28(15-10-24)42-19-17-23-7-12-27(37)13-8-23/h7-16,20,34,39H,5-6,17-19,21H2,1-4H3,(H,40,41)/t34-/m0/s1
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<100n/an/a7.55n/a



ViiV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10106504 (2018)


BindingDB Entry DOI: 10.7270/Q2BC41K2
More data for this
Ligand-Target Pair