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BDBM293279 US10106504, Example 16

SMILES: Cc1nc(COCC2COC2)c(-c2ccc(OCCc3ccc(F)cc3)cc2)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O

InChI Key: InChIKey=FHEXFOGJSANGMM-LHEWISCISA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293279   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HIV-1 Protease Chain A


(Human immunodeficiency virus type 1)		BDBM293279
PNG
(US10106504, Example 16)
Show SMILES Cc1nc(COCC2COC2)c(-c2ccc(OCCc3ccc(F)cc3)cc2)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C40H44FNO7/c1-25-35(38(39(43)44)49-40(2,3)4)37(30-11-16-34-29(20-30)6-5-18-48-34)36(33(42-25)24-46-23-27-21-45-22-27)28-9-14-32(15-10-28)47-19-17-26-7-12-31(41)13-8-26/h7-16,20,27,38H,5-6,17-19,21-24H2,1-4H3,(H,43,44)/t38-/m0/s1
PDB

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AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<100n/an/a7.55n/a



ViiV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10106504 (2018)


BindingDB Entry DOI: 10.7270/Q2BC41K2
More data for this
Ligand-Target Pair