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SMILES: Cc1nc(C)c(-c2ccc3CN(Cc4ccc(F)cc4)CCc3c2)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O

InChI Key: InChIKey=XBQMQSOAPJZBJL-BHVANESWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293283   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [489-587,Q496K]


(Human immunodeficiency virus type 1)		BDBM293283
PNG
(US10106504, Example 20)
Show SMILES Cc1nc(C)c(-c2ccc3CN(Cc4ccc(F)cc4)CCc3c2)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Show InChI InChI=1S/C38H41FN2O4/c1-23-33(28-10-11-30-22-41(17-16-26(30)19-28)21-25-8-13-31(39)14-9-25)35(29-12-15-32-27(20-29)7-6-18-44-32)34(24(2)40-23)36(37(42)43)45-38(3,4)5/h8-15,19-20,36H,6-7,16-18,21-22H2,1-5H3,(H,42,43)/t36-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<100n/an/a7.55n/a



ViiV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10106504 (2018)


BindingDB Entry DOI: 10.7270/Q2BC41K2
More data for this
Ligand-Target Pair