BDBM293284 US10106504, Example 21

SMILES: Cc1nc(C)c(-c2ccc3CNCCc3c2)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O

InChI Key: InChIKey=RINMXMLXSGZUAE-LJAQVGFWSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Protease Chain A (Human immunodeficiency virus type 1)	BDBM293284 (US10106504, Example 21) Show SMILES Cc1nc(C)c(-c2ccc3CNCCc3c2)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O |r| Show InChI InChI=1S/C31H36N2O4/c1-18-26(22-8-9-24-17-32-13-12-20(24)15-22)28(23-10-11-25-21(16-23)7-6-14-36-25)27(19(2)33-18)29(30(34)35)37-31(3,4)5/h8-11,15-16,29,32H,6-7,12-14,17H2,1-5H3,(H,34,35)/t29-/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.77E+3	n/a	n/a	7.55	n/a
ViiV HEALTHCARE UK (NO.5) LIMITED US Patent					Assay Description A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...				US Patent US10106504 (2018) BindingDB Entry DOI: 10.7270/Q2BC41K2
					More data for this Ligand-Target Pair
HIV-1 Protease Chain A (Human immunodeficiency virus type 1)	BDBM293284 (US10106504, Example 21) Show SMILES Cc1nc(C)c(-c2ccc3CNCCc3c2)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O |r| Show InChI InChI=1S/C31H36N2O4/c1-18-26(22-8-9-24-17-32-13-12-20(24)15-22)28(23-10-11-25-21(16-23)7-6-14-36-25)27(19(2)33-18)29(30(34)35)37-31(3,4)5/h8-11,15-16,29,32H,6-7,12-14,17H2,1-5H3,(H,34,35)/t29-/m0/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	7.55	n/a
ViiV HEALTHCARE UK (NO.5) LIMITED US Patent					Assay Description A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...				US Patent US10106504 (2018) BindingDB Entry DOI: 10.7270/Q2BC41K2
					More data for this Ligand-Target Pair