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BDBM293319 US10106504, Example 56

SMILES: Cc1cc(F)ccc1CN1CCc2cc(ccc2C1)-c1c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c1-c1ccc2OCCCc2c1

InChI Key: InChIKey=MTPYOWBXCTUCRY-QNGWXLTQSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293319   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HIV-1 Protease Chain A


(Human immunodeficiency virus type 1)		BDBM293319
PNG
(US10106504, Example 56)
Show SMILES Cc1cc(F)ccc1CN1CCc2cc(ccc2C1)-c1c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c1-c1ccc2OCCCc2c1 |r|
Show InChI InChI=1S/C39H43FN2O4/c1-23-18-32(40)13-11-30(23)21-42-16-15-26-19-28(9-10-31(26)22-42)34-24(2)41-25(3)35(37(38(43)44)46-39(4,5)6)36(34)29-12-14-33-27(20-29)8-7-17-45-33/h9-14,18-20,37H,7-8,15-17,21-22H2,1-6H3,(H,43,44)/t37-/m0/s1
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<100n/an/a7.55n/a



ViiV HEALTHCARE UK (NO.5) LIMITED

US Patent


Assay Description
A recombinant NL-RLuc proviral clone was constructed in which a section of the nef gene from NL4-3 was replaced with the Renilla Luciferase gene. Thi...

US Patent US10106504 (2018)


BindingDB Entry DOI: 10.7270/Q2BC41K2
More data for this
Ligand-Target Pair