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BDBM29332 triphenylmethane derivative, 4

SMILES: OC(=O)c1cc(Nc2ccc(cc2)C(Cl)(c2ccccc2)c2ccc(Nc3ccc(Cl)c(c3)C(O)=O)cc2)ccc1Cl

InChI Key: InChIKey=XBBQRUDAAHWPBS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29332   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis C virus genotype 1b (isolate Taiwan))		BDBM29332
PNG
(triphenylmethane derivative, 4)
Show SMILES OC(=O)c1cc(Nc2ccc(cc2)C(Cl)(c2ccccc2)c2ccc(Nc3ccc(Cl)c(c3)C(O)=O)cc2)ccc1Cl
Show InChI InChI=1S/C33H23Cl3N2O4/c34-29-16-14-25(18-27(29)31(39)40)37-23-10-6-21(7-11-23)33(36,20-4-2-1-3-5-20)22-8-12-24(13-9-22)38-26-15-17-30(35)28(19-26)32(41)42/h1-19,37-38H,(H,39,40)(H,41,42)
PDB
MMDB

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PubMed
n/an/a 2.97E+4n/an/an/an/a7.022



National Taiwan University



Assay Description
The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...

J Med Chem 52: 2716-23 (2009)


Article DOI: 10.1021/jm8011905
BindingDB Entry DOI: 10.7270/Q2RF5SBT
More data for this
Ligand-Target Pair