BDBM293670 3-({[(1R)-6-[methyl(pyridin-3-yl)amino]-1,2,3,4-::US10106534, Example 12

SMILES: CN(c1cccnc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCCc2c1

InChI Key: InChIKey=SMZIDIXJQQKOIG-KRWDZBQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293670 (3-({[(1R)-6-[methyl(pyridin-3-yl)amino]-1,2,3,4- |...) Show SMILES CN(c1cccnc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCCc2c1 |r| Show InChI InChI=1S/C23H24N4O2/c1-27(19-6-3-10-24-14-19)18-7-8-20-16(12-18)4-2-5-17(20)13-26-22-15-25-11-9-21(22)23(28)29/h3,6-12,14-15,17,26H,2,4-5,13H2,1H3,(H,28,29)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair