BDBM293677 3-({[(4R)-7-[(2-fluorophenyl)(methyl)amino]-3,4-dihydro-2H-1-::US10106534, Example 19

SMILES: CN(c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1)c1ccccc1F

InChI Key: InChIKey=SKQURSROZMRXIJ-HNNXBMFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293677   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293677 (3-({[(4R)-7-[(2-fluorophenyl)(methyl)amino]-3,4-di...) Show SMILES CN(c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1)c1ccccc1F |r| Show InChI InChI=1S/C23H22FN3O3/c1-27(21-5-3-2-4-19(21)24)16-6-7-17-15(9-11-30-22(17)12-16)13-26-20-14-25-10-8-18(20)23(28)29/h2-8,10,12,14-15,26H,9,11,13H2,1H3,(H,28,29)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair