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SMILES: CNC(=O)[C@@H]1CCCN1C(=O)Cc1ccc2OCOc2c1

InChI Key: InChIKey=YWQAHYSADGEEFT-NSHDSACASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM29368 (proline scaffold, 17) Show SMILES CNC(=O)[C@@H]1CCCN1C(=O)Cc1ccc2OCOc2c1 |r| Show InChI InChI=1S/C15H18N2O4/c1-16-15(19)11-3-2-6-17(11)14(18)8-10-4-5-12-13(7-10)21-9-20-12/h4-5,7,11H,2-3,6,8-9H2,1H3,(H,16,19)/t11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	>1.00E+6	n/a	n/a	n/a	7.4	37
University of Kalmar					Assay Description SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...				J Med Chem 52: 2708-15 (2009) Article DOI: 10.1021/jm8011849 BindingDB Entry DOI: 10.7270/Q2H130B7
					More data for this Ligand-Target Pair