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SMILES: Cc1cccc(c1)-c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key: InChIKey=DFSHSQWFAPRJQC-SFHVURJKSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293688   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 4C


(Homo sapiens (Human))		BDBM293688
PNG
(3-({[(4R)-7-(3-methylphenyl)-3,4-dihydro-2H-1-benz...)
Show SMILES Cc1cccc(c1)-c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1 |r|
Show InChI InChI=1S/C23H22N2O3/c1-15-3-2-4-16(11-15)17-5-6-19-18(8-10-28-22(19)12-17)13-25-21-14-24-9-7-20(21)23(26)27/h2-7,9,11-12,14,18,25H,8,10,13H2,1H3,(H,26,27)/t18-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10106534 (2018)


BindingDB Entry DOI: 10.7270/Q2JW8GZX
More data for this
Ligand-Target Pair