BDBM293691 3-({[(4S)-7-(thiophen-3-yl)-3,4-dihydro-2H-1-benzopyran-4-::US10106534, Example 33

SMILES: OC(=O)c1ccncc1NC[C@H]1CCOc2cc(ccc12)-c1ccsc1

InChI Key: InChIKey=PWVSOZJTWGBRAX-CQSZACIVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
jmjd3 (Homo sapiens (Human))	BDBM293691 (3-({[(4S)-7-(thiophen-3-yl)-3,4-dihydro-2H-1-benzo...) Show SMILES OC(=O)c1ccncc1NC[C@H]1CCOc2cc(ccc12)-c1ccsc1 |r| Show InChI InChI=1S/C20H18N2O3S/c23-20(24)17-3-6-21-11-18(17)22-10-14-4-7-25-19-9-13(1-2-16(14)19)15-5-8-26-12-15/h1-3,5-6,8-9,11-12,14,22H,4,7,10H2,(H,23,24)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293691 (3-({[(4S)-7-(thiophen-3-yl)-3,4-dihydro-2H-1-benzo...) Show SMILES OC(=O)c1ccncc1NC[C@H]1CCOc2cc(ccc12)-c1ccsc1 |r| Show InChI InChI=1S/C20H18N2O3S/c23-20(24)17-3-6-21-11-18(17)22-10-14-4-7-25-19-9-13(1-2-16(14)19)15-5-8-26-12-15/h1-3,5-6,8-9,11-12,14,22H,4,7,10H2,(H,23,24)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair