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SMILES: OC(=O)c1ccncc1NC[C@@H]1CCOc2cc(ccc12)-c1cc(F)ccc1Cl

InChI Key: InChIKey=QMFLFONTKPDYMJ-AWEZNQCLSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293703   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 4C


(Homo sapiens (Human))		BDBM293703
PNG
(3-({[(4R)-7-(2-chloro-5-fluorophenyl)-3,4-dihydro-...)
Show SMILES OC(=O)c1ccncc1NC[C@@H]1CCOc2cc(ccc12)-c1cc(F)ccc1Cl |r|
Show InChI InChI=1S/C22H18ClFN2O3/c23-19-4-2-15(24)10-18(19)13-1-3-16-14(6-8-29-21(16)9-13)11-26-20-12-25-7-5-17(20)22(27)28/h1-5,7,9-10,12,14,26H,6,8,11H2,(H,27,28)/t14-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10106534 (2018)


BindingDB Entry DOI: 10.7270/Q2JW8GZX
More data for this
Ligand-Target Pair