null
SMILES: OC(=O)c1ccncc1NC[C@@H]1CCOc2cc(ccc12)-c1ccccc1[B](F)(F)F
InChI Key: InChIKey=QTRNTLADYMCEIF-HNNXBMFYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM293704 (3-({[(4R)-7-[2-(trifluoromethyl)phenyl]-3,4-dihydr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | 25 |
Celgene Quanticel Research, Inc. US Patent | Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ... | US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX | |||||||||||
More data for this Ligand-Target Pair |