BDBM293707 3-({[7-(thiophen-2-ylsulfanyl)-3,4-dihydro-2H-1-benzopyran-4-::US10106534, Example 49

SMILES: OC(=O)c1ccncc1NCC1CCOc2cc(Sc3cccs3)ccc12

InChI Key: InChIKey=IVORPNIEGOAXQG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293707   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293707 (3-({[7-(thiophen-2-ylsulfanyl)-3,4-dihydro-2H-1-be...) Show SMILES OC(=O)c1ccncc1NCC1CCOc2cc(Sc3cccs3)ccc12 Show InChI InChI=1S/C20H18N2O3S2/c23-20(24)16-5-7-21-12-17(16)22-11-13-6-8-25-18-10-14(3-4-15(13)18)27-19-2-1-9-26-19/h1-5,7,9-10,12-13,22H,6,8,11H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair