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SMILES: Cc1ccccc1Sc1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key: InChIKey=HESGFDYKSUOOBB-INIZCTEOSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293709   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 4C


(Homo sapiens (Human))		BDBM293709
PNG
(3-({[(4R)-7-[(2-methylphenyl)sulfanyl]-3,4-dihydro...)
Show SMILES Cc1ccccc1Sc1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1 |r|
Show InChI InChI=1S/C23H22N2O3S/c1-15-4-2-3-5-22(15)29-17-6-7-18-16(9-11-28-21(18)12-17)13-25-20-14-24-10-8-19(20)23(26)27/h2-8,10,12,14,16,25H,9,11,13H2,1H3,(H,26,27)/t16-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...

US Patent US10106534 (2018)


BindingDB Entry DOI: 10.7270/Q2JW8GZX
More data for this
Ligand-Target Pair