BDBM293710 3-({[(4S)-7-[(3-fluorophenyl)sulfanyl]-3,4-dihydro-2H-1-::US10106534, Example 52

SMILES: OC(=O)c1ccncc1NC[C@H]1CCOc2cc(Sc3cccc(F)c3)ccc12

InChI Key: InChIKey=MLMKCAMJJOYOSV-CQSZACIVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
jmjd3 (Homo sapiens (Human))	BDBM293710 (3-({[(4S)-7-[(3-fluorophenyl)sulfanyl]-3,4-dihydro...) Show SMILES OC(=O)c1ccncc1NC[C@H]1CCOc2cc(Sc3cccc(F)c3)ccc12 |r| Show InChI InChI=1S/C22H19FN2O3S/c23-15-2-1-3-16(10-15)29-17-4-5-18-14(7-9-28-21(18)11-17)12-25-20-13-24-8-6-19(20)22(26)27/h1-6,8,10-11,13-14,25H,7,9,12H2,(H,26,27)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293710 (3-({[(4S)-7-[(3-fluorophenyl)sulfanyl]-3,4-dihydro...) Show SMILES OC(=O)c1ccncc1NC[C@H]1CCOc2cc(Sc3cccc(F)c3)ccc12 |r| Show InChI InChI=1S/C22H19FN2O3S/c23-15-2-1-3-16(10-15)29-17-4-5-18-14(7-9-28-21(18)11-17)12-25-20-13-24-8-6-19(20)22(26)27/h1-6,8,10-11,13-14,25H,7,9,12H2,(H,26,27)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair