BDBM293789 3-({[(4R)-7-[(2,3-dihydro-1H-inden-5-yl)(methyl)amino]-3,4-::US10106534, Example 131

SMILES: CN(Cc1ccc2CCCc2c1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key: InChIKey=HHRDCFZSYMXEIS-NRFANRHFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
jmjd3 (Homo sapiens (Human))	BDBM293789 (3-({[(4R)-7-[(2,3-dihydro-1H-inden-5-yl)(methyl)am...) Show SMILES CN(Cc1ccc2CCCc2c1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1 |r| Show InChI InChI=1S/C27H29N3O3/c1-30(17-18-5-6-19-3-2-4-20(19)13-18)22-7-8-23-21(10-12-33-26(23)14-22)15-29-25-16-28-11-9-24(25)27(31)32/h5-9,11,13-14,16,21,29H,2-4,10,12,15,17H2,1H3,(H,31,32)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293789 (3-({[(4R)-7-[(2,3-dihydro-1H-inden-5-yl)(methyl)am...) Show SMILES CN(Cc1ccc2CCCc2c1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1 |r| Show InChI InChI=1S/C27H29N3O3/c1-30(17-18-5-6-19-3-2-4-20(19)13-18)22-7-8-23-21(10-12-33-26(23)14-22)15-29-25-16-28-11-9-24(25)27(31)32/h5-9,11,13-14,16,21,29H,2-4,10,12,15,17H2,1H3,(H,31,32)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair