BDBM293803 3-({[(4R)-7-[methyl(5-methylpyridin-2-yl)amino]-3,4-dihydro-2H-::US10106534, Example 145

SMILES: CN(c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1)c1ccc(C)cn1

InChI Key: InChIKey=RGJVLNLBHVELQL-INIZCTEOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293803   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
jmjd3 (Homo sapiens (Human))	BDBM293803 (3-({[(4R)-7-[methyl(5-methylpyridin-2-yl)amino]-3,...) Show SMILES CN(c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1)c1ccc(C)cn1 |r| Show InChI InChI=1S/C23H24N4O3/c1-15-3-6-22(26-12-15)27(2)17-4-5-18-16(8-10-30-21(18)11-17)13-25-20-14-24-9-7-19(20)23(28)29/h3-7,9,11-12,14,16,25H,8,10,13H2,1-2H3,(H,28,29)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293803 (3-({[(4R)-7-[methyl(5-methylpyridin-2-yl)amino]-3,...) Show SMILES CN(c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1)c1ccc(C)cn1 |r| Show InChI InChI=1S/C23H24N4O3/c1-15-3-6-22(26-12-15)27(2)17-4-5-18-16(8-10-30-21(18)11-17)13-25-20-14-24-9-7-19(20)23(28)29/h3-7,9,11-12,14,16,25H,8,10,13H2,1-2H3,(H,28,29)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair