BDBM293841 3-({[(4R)-7-{[4-(azetidin-1-yl)phenyl](methyl)amino}-3,4-dihydro-::US10106534, Example 183

SMILES: CN(c1ccc(cc1)N1CCC1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key: InChIKey=OKFZDWBVLBCSAL-SFHVURJKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM293841 (3-({[(4R)-7-{[4-(azetidin-1-yl)phenyl](methyl)amin...) Show SMILES CN(c1ccc(cc1)N1CCC1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1 |r| Show InChI InChI=1S/C26H28N4O3/c1-29(19-3-5-20(6-4-19)30-12-2-13-30)21-7-8-22-18(10-14-33-25(22)15-21)16-28-24-17-27-11-9-23(24)26(31)32/h3-9,11,15,17-18,28H,2,10,12-14,16H2,1H3,(H,31,32)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293841 (3-({[(4R)-7-{[4-(azetidin-1-yl)phenyl](methyl)amin...) Show SMILES CN(c1ccc(cc1)N1CCC1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1 |r| Show InChI InChI=1S/C26H28N4O3/c1-29(19-3-5-20(6-4-19)30-12-2-13-30)21-7-8-22-18(10-14-33-25(22)15-21)16-28-24-17-27-11-9-23(24)26(31)32/h3-9,11,15,17-18,28H,2,10,12-14,16H2,1H3,(H,31,32)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair