null

SMILES: CN(c1ccc(CC(F)(F)F)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key: InChIKey=HXCHGSSTPPJJKH-KRWDZBQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293850   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM293850 (3-({[(4R)-7-{methyl[4-(2,2,2-trifluoroethyl)phenyl...) Show SMILES CN(c1ccc(CC(F)(F)F)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1 |r| Show InChI InChI=1S/C25H24F3N3O3/c1-31(18-4-2-16(3-5-18)13-25(26,27)28)19-6-7-20-17(9-11-34-23(20)12-19)14-30-22-15-29-10-8-21(22)24(32)33/h2-8,10,12,15,17,30H,9,11,13-14H2,1H3,(H,32,33)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293850 (3-({[(4R)-7-{methyl[4-(2,2,2-trifluoroethyl)phenyl...) Show SMILES CN(c1ccc(CC(F)(F)F)cc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1 |r| Show InChI InChI=1S/C25H24F3N3O3/c1-31(18-4-2-16(3-5-18)13-25(26,27)28)19-6-7-20-17(9-11-34-23(20)12-19)14-30-22-15-29-10-8-21(22)24(32)33/h2-8,10,12,15,17,30H,9,11,13-14H2,1H3,(H,32,33)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair