BDBM293851 3-({[(1R)-6-{[4-(1H-imidazol-1-yl)phenyl](methyl)amino}-1,2,3,4-::US10106534, Example 193

SMILES: CN(c1ccc(cc1)-n1ccnc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCCc2c1

InChI Key: InChIKey=UQLXXXATWVZZPZ-FQEVSTJZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293851   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
jmjd3 (Homo sapiens (Human))	BDBM293851 (3-({[(1R)-6-{[4-(1H-imidazol-1-yl)phenyl](methyl)a...) Show SMILES CN(c1ccc(cc1)-n1ccnc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCCc2c1 |r| Show InChI InChI=1S/C27H27N5O2/c1-31(21-5-7-22(8-6-21)32-14-13-29-18-32)23-9-10-24-19(15-23)3-2-4-20(24)16-30-26-17-28-12-11-25(26)27(33)34/h5-15,17-18,20,30H,2-4,16H2,1H3,(H,33,34)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293851 (3-({[(1R)-6-{[4-(1H-imidazol-1-yl)phenyl](methyl)a...) Show SMILES CN(c1ccc(cc1)-n1ccnc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCCc2c1 |r| Show InChI InChI=1S/C27H27N5O2/c1-31(21-5-7-22(8-6-21)32-14-13-29-18-32)23-9-10-24-19(15-23)3-2-4-20(24)16-30-26-17-28-12-11-25(26)27(33)34/h5-15,17-18,20,30H,2-4,16H2,1H3,(H,33,34)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
					More data for this Ligand-Target Pair