BDBM293862 3-({[(4R)-7-{methyl[4-(1-methyl-1,2,3,6-tetrahydropyridin-4-::US10106534, Example 204
SMILES: CN(c1ccc(cc1)C1=CCN(C)CC1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1
InChI Key: InChIKey=MDGUBTPVCAYRES-QFIPXVFZSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM293862 (3-({[(4R)-7-{methyl[4-(1-methyl-1,2,3,6-tetrahydro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | 25 |
Celgene Quanticel Research, Inc. US Patent | Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ... | US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX | |||||||||||
More data for this Ligand-Target Pair |