BDBM293863 3-({[(4R)-7-{methyl[4-(1-methylpiperidin-4-yl)phenyl]amino}-3,4-::US10106534, Example 205

SMILES: CN(c1ccc(cc1)C1CCN(C)CC1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key: InChIKey=UVDZJDPEMLCPFR-QFIPXVFZSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM293863 (3-({[(4R)-7-{methyl[4-(1-methylpiperidin-4-yl)phen...) Show SMILES CN(c1ccc(cc1)C1CCN(C)CC1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1 |r| Show InChI InChI=1S/C29H34N4O3/c1-32-14-10-21(11-15-32)20-3-5-23(6-4-20)33(2)24-7-8-25-22(12-16-36-28(25)17-24)18-31-27-19-30-13-9-26(27)29(34)35/h3-9,13,17,19,21-22,31H,10-12,14-16,18H2,1-2H3,(H,34,35)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	25
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10106534 (2018) BindingDB Entry DOI: 10.7270/Q2JW8GZX
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