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SMILES: Cc1c(F)cccc1[C@@]1(CCC(=C1)c1cnn(CC(F)(F)F)c1)C(=O)NO

InChI Key: InChIKey=UEBUMEGYICYBBJ-KRWDZBQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293902   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 4 (Homo sapiens (Human))	BDBM293902 ((S)-1-(3-Fluoro-2- methylphenyl)-N- hydroxy-3-(1-(...) Show SMILES Cc1c(F)cccc1[C@@]1(CCC(=C1)c1cnn(CC(F)(F)F)c1)C(=O)NO |r,c:12| Show InChI InChI=1S/C18H17F4N3O2/c1-11-14(3-2-4-15(11)19)17(16(26)24-27)6-5-12(7-17)13-8-23-25(9-13)10-18(20,21)22/h2-4,7-9,27H,5-6,10H2,1H3,(H,24,26)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description 2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...				US Patent US9617259 (2017) BindingDB Entry DOI: 10.7270/Q2DN4743
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM293902 ((S)-1-(3-Fluoro-2- methylphenyl)-N- hydroxy-3-(1-(...) Show SMILES Cc1c(F)cccc1[C@@]1(CCC(=C1)c1cnn(CC(F)(F)F)c1)C(=O)NO |r,c:12| Show InChI InChI=1S/C18H17F4N3O2/c1-11-14(3-2-4-15(11)19)17(16(26)24-27)6-5-12(7-17)13-8-23-25(9-13)10-18(20,21)22/h2-4,7-9,27H,5-6,10H2,1H3,(H,24,26)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
CHDI FOUNDATION, INC. US Patent					Assay Description 5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...				US Patent US10106535 (2018) BindingDB Entry DOI: 10.7270/Q2F47R6G
					More data for this Ligand-Target Pair