BDBM293927 US10106552, Compound 2

SMILES: CC1(C)CCc2nc3sc(C(N)=O)c(N)c3c(-c3ccc(Cl)o3)c2C1

InChI Key: InChIKey=BHABBQIXMTZLIW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM293927 (US10106552, Compound 2) Show SMILES CC1(C)CCc2nc3sc(C(N)=O)c(N)c3c(-c3ccc(Cl)o3)c2C1 Show InChI InChI=1S/C18H18ClN3O2S/c1-18(2)6-5-9-8(7-18)12(10-3-4-11(19)24-10)13-14(20)15(16(21)23)25-17(13)22-9/h3-4H,5-7,20H2,1-2H3,(H2,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Longevica Pharmaceuticals, Inc. US Patent					Assay Description To determine the IC50 of compounds of the invention, recombinant eEF2K was diluted in an assay buffer in the presence of calmodulin, a calcium-bindin...				US Patent US10106552 (2018) BindingDB Entry DOI: 10.7270/Q25M67SV
					More data for this Ligand-Target Pair