BDBM293935 US10106552, Compound 10

SMILES: CC1(C)CCc2c(C1)nc1sc(C(N)=O)c(N)c1c2-c1ccco1

InChI Key: InChIKey=BPTFGRHJADOZNR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM293935 (US10106552, Compound 10) Show SMILES CC1(C)CCc2c(C1)nc1sc(C(N)=O)c(N)c1c2-c1ccco1 Show InChI InChI=1S/C18H19N3O2S/c1-18(2)6-5-9-10(8-18)21-17-13(12(9)11-4-3-7-23-11)14(19)15(24-17)16(20)22/h3-4,7H,5-6,8,19H2,1-2H3,(H2,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Longevica Pharmaceuticals, Inc. US Patent					Assay Description To determine the IC50 of compounds of the invention, recombinant eEF2K was diluted in an assay buffer in the presence of calmodulin, a calcium-bindin...				US Patent US10106552 (2018) BindingDB Entry DOI: 10.7270/Q25M67SV
					More data for this Ligand-Target Pair